Tuesday, 18th February
46th Lorne Genome Conference 2025
Days
Sunday, 16th February
Monday, 17th February
Tuesday, 18th February
Wednesday, 19th February
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Speakers
Session 7 - Transcriptional regulation
9:00AM - 10:45AM
Tuesday, 18th February
Heritage Ballroom
Chairs: Lee Wong & Davis McCarthy
Evolutionarily conserved cis regulatory elements in cardiac development and congenital heart disease
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Michael D Wilson
Disruption of the Integrator complex triggers the Integrated Stress Response through formation of double-stranded RNA
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Karen Adelman
CDK11-dependent control of RNA polymerase II pausing at a new transcription cycle checkpoint
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Jennifer Devlin
A P300/SF3B3 dependent checkpoint for transcriptional co-activation
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Dane Vassiliadis
Morning Tea
10:45AM - 11:15AM
Tuesday, 18th February
Convention Centre
Concurrent Session 8A - Gene Expression and Epigenetics
11:15AM - 1:00PM
Tuesday, 18th February
Heritage Ballroom
Chairs: Carolyn de Graaf & Charles Bell
Epigenetic partner proteins guide transcription factors to their targets
in vivo
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Manan Shah
Epigenetic regulation in the female immune system
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Ksenia Skvortsova
Imaging-based chromatin and epigenetic age.
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Alexey Terskikh
Unravelling the inactive X: variation in epigenetic modes across tissues
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Quentin Gouil
Insights into two Tudor domain proteins and their functions in
C. elegans
germline epigenetic pathways
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Carlotta Wills
DOT1L functions as a transcriptional memory component of the MLL-Polycomb axis
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Daniel Neville
‘X’ploring the role of epigenetic modifier p400 in X chromosome inactivation
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Boya Zhang
Concurrent Session 8B - Genome in Development
11:15AM - 1:00PM
Tuesday, 18th February
Heritage Room
Chairs: Tanya Soboleva & John Bowman
Constructing a pangenome reference of African foragers to improve a catalogue of early diverged contemporary human genome variation
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Weerachai Jaraltledsiri
Spatially charting the developing fat-tailed dunnart
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Monika Mohenska
ZMYND8: An epigenetic regulator of the dorsal-ventral patterning of brain development
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Juli Wang
Uncovering the Functions of Alternative Splicing in EMT using RNA-Targeting CRISPR Technology
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Jasleen Rajpal
Dissecting the roles of Nr6a1 at early stages of the mouse hindlimb development
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Edwina McGlinn
Investigating the epigenetic regulator SMCHD1 as a potential therapeutic target for the treatment of Prader-Willi Syndrome
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Megan Iminitoff
Allosteric effectors of PRC2 synergise to restrict the spread of Polycomb domains
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Samuel C Agius
Lunch
1:00PM - 2:30PM
Tuesday, 18th February
Convention Centre
Annual General Meeting
1:00PM - 1:45PM
Tuesday, 18th February
Heritage Ballroom
Student & Invited Speaker Lunch
1:00PM - 1:45PM
Tuesday, 18th February
Professional Development Session
1:45PM - 2:30PM
Tuesday, 18th February
Heritage Ballroom
Session 9 - Functional Genomics
2:30PM - 3:55PM
Tuesday, 18th February
Heritage Ballroom
Chairs: Alyson Ashe & Andrew Keniry
Sponsored by:
Chromatin Regulation and Longevity in C. elegans
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Siu Sylvia Lee
Functional characterization and therapeutic targeting of gene regulatory elements
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Nadav Ahituv
A broad-acting venom antidote identified through whole-genome CRISPR screening
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Tian Y Du
Afternoon Tea
3:55PM - 4:30PM
Tuesday, 18th February
Convention Centre
Session 10 - Chromatin and non-coding RNA
4:30PM - 6:30PM
Tuesday, 18th February
Heritage Ballroom
Chairs: Stacey Edwards & Chuck Herring
Polycomb Repressive Complexes in Development and Cancer
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Adrian Bracken
Noncoding RNA roles in the coordination of DNA replication in human cells
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Maite Huarte
“Structure and function of synthetic euchromatin fibres”
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Nick Gilbert
Chromatin tethering by the Trithorax homolog MLL during the ESC naive to primed transition
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Francis Stewart
Conference Dinner
7:00PM - 9:00PM
Tuesday, 18th February
Lorne Common
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